Well, it's illegal to use a computer in most jurisdictions, so it'd be stupid. If you're gonna cheat, you might as well learn to muck or mark cards; huge edge, hard to catch.
BUT, it would probably center on finding biased wheels. Personally, I don't believe it, because the house edge is too high to find a wheel that biased. I might believe it in a few rare cases, but I doubt it. Big 6 wheel is more plausible...