Different playing rules will effect a few basic strategy plays, single / multi-deck for example. For the newby the "rule of thumb" is to first learn basic strategy for the common game at your favorite casino, or simply a six-deck shoe game. When you have mastered this, learning the few alterations to basic strategy for another set of rules is a breeze. Please note, even if you play basic strategy for a six-deck at a two deck game you are giving up very little to the house. ZG is correct the basic strategy generator on this site will give you the correct BS for any set of rules.