No it doesn't. BS for four and six decks games are the same, and if you use a balanced count, Hi-Lo (as per the movie "21") being the most common, the principle and indices are the same. I'm not aware that there are any four-deck specific indices to apply?
Visit Napoleons in Leicester Square, London, or Sheffield to find four deck shoe dealt blackjack. The pen in the London venue can be pretty awful though and render the game unbeatable, despite the four decks.